Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066065 | 0.91 | XIAP (0.57) | XIAPOPRM1BIRC3BIRC2 | |
| SCHEMBL10081371 | 0.89 | XIAP (0.65) | XIAPBIRC3BIRC2 | |
| SCHEMBL13119703 | 0.88 | XIAP (0.53) | XIAPBIRC3BIRC2 | |
| SCHEMBL10066062 | 0.88 | XIAP (0.55) | XIAPACEBIRC3BIRC2 | |
| SCHEMBL10081797 | 0.88 | XIAP (0.55) | XIAPACEBIRC3BIRC2 | |
| SCHEMBL3439047 | 0.88 | XIAP (0.53) | XIAPOPRM1BIRC3BIRC2 | |
| SCHEMBL10082409 | 0.87 | OPRM1 (0.51) | OPRM1ALDH1A1LMNAMAPT | |
| SCHEMBL10066063 | 0.87 | OPRM1 (0.51) | OPRM1ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL895599 | 0.86 | OPRM1 (0.51) | OPRM1ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL895597 | 0.86 | OPRM1 (0.51) | OPRM1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | JOYANT PHARMACEUTICALS, INC. | 2013-10-24 | — | — | US | disclosed |
| US-8222291-B2 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-7807699-B2 | Dimeric pyrrolidine amide-containing small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| EP-1996184-A2 | SMALL MOLECULE APOPTOSIS PROMOTERS | Joyant Pharmaceuticals, Inc. (US) | 2008-12-03 | — | — | EP | disclosed |
| US-20080051389-A1 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. | 2008-02-28 | — | — | US | disclosed |
| WO-2007136921-A2 | SMALL MOLECULE APOPTOSIS PROMOTERS | JOYANT PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | BID, BAD, BAX | XIAP 31/4885OPRM1 4408/4885ACE 4776/4885 |
| US-20080051389-A1 | Small molecule apoptosis promoters | BID, BAD, BAX | XIAP 31/4885OPRM1 4408/4885ACE 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.