SCHEMBL3439067

SCHEMBL3439067

O=C(COCC(=O)OCC(=O)Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl)OCC(=O)Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.46
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TTR P02766 5/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 2/20 0.45
NR1I2 O75469 1/20 0.45
LMNA P02545 1/20 0.45
PGR P06401 1/20 0.45
HSP90AA1 P07900 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
HSPA5 P11021 1/20 0.45
CBR1 P16152 1/20 0.45
TBXA2R P21731 1/20 0.45
SLC6A2 P23975 1/20 0.45
AGTR1 P30556 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CHRM1 P11229 1/20 0.45
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3438990 0.94 TTR (0.50) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL12160410 0.87 TTR (0.46) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL3438991 0.84 TDP1 (0.51) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL2116273 0.82 TDP1 (0.50) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL2118699 0.82 TDP1 (0.48) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL2117927 0.82 CHRM1 (0.50) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL3439029 0.82 MAPT (0.51) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL8743430 0.81 TTR (0.51) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL2118037 0.81 TTR (0.51) TDP1ALDH1A1L3MBTL1TTRMAPT
SCHEMBL7072347 0.80 TTR (0.52) TDP1ALDH1A1L3MBTL1TTRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399696-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2013-03-19 US disclosed
US-8399696-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2013-03-19 US disclosed
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-11-15 US disclosed
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-11-15 US disclosed
US-8232422-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2012-07-31 US disclosed
US-8232422-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2012-07-31 US disclosed
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 TDP1 1065/4885ALDH1A1 4403/4885L3MBTL1 1378/4885
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 TDP1 1065/4885ALDH1A1 4403/4885L3MBTL1 1378/4885
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 TDP1 1065/4885ALDH1A1 4403/4885L3MBTL1 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.