SCHEMBL3439029

SCHEMBL3439029

CCCCCCCCCCCCCCCCCC(=O)OCC(=O)Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
ALDH1A1 P00352 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPK1 P28482 1/20 0.47
HPGD P15428 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
ALOX15 P16050 1/20 0.44
TP53 P04637 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TTR P02766 1/20 0.42
PAM P19021 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14332348 0.92 MAPT (0.53) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL7067530 0.91 ALOX15 (0.52) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10895571 0.86 ALDH1A1 (0.55) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL3438988 0.85 MAPT (0.52) MAPTALDH1A1TDP1L3MBTL1HPGD
SCHEMBL10881492 0.85 ALDH1A1 (0.54) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10879742 0.85 ALDH1A1 (0.54) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10884052 0.84 MAPT (0.49) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL11113053 0.84 MAPT (0.49) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10883853 0.82 MAPT (0.48) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL3439067 0.82 TDP1 (0.46) MAPTALDH1A1TDP1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399696-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2013-03-19 US disclosed
US-8399696-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2013-03-19 US disclosed
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-11-15 US disclosed
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-11-15 US disclosed
US-8232422-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2012-07-31 US disclosed
US-8232422-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2012-07-31 US disclosed
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 MAPT 603/4885ALDH1A1 4403/4885TDP1 1065/4885
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 MAPT 603/4885ALDH1A1 4403/4885TDP1 1065/4885
US-20120289614-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 MAPT 603/4885ALDH1A1 4403/4885TDP1 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.