Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30981311 | 0.86 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL28186774 | 0.82 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL25845507 | 0.82 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL25189631 | 0.82 | MEN1 (0.60) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL13114892 | 0.82 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL27832 | 0.81 | SIRT6 (0.59) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL4347097 | 0.81 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL4399969 | 0.80 | MAPT (0.70) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL25189146 | 0.80 | MEN1 (0.57) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL29104 | 0.79 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2ASIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| EP-2284166-A1 | Arylsulfonamides with analgetic activity | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009021758-A1 | ARYLSULFONAMIDES HAVING AN ANALGESIC EFFECT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021946-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| EP-2025675-A1 | Arylsulfonamides with analgetic activity | Boehringer Ingelheim International GmbH (DE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008022945-A1 | ARYL SULFONAMIDES WITH AN ANALGESIC ACTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |