Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 13/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12916582 | 0.93 | MAPT (0.41) | L3MBTL1MAPTALDH1A1KMT2AGAA | |
| SCHEMBL12010119 | 0.92 | BDKRB1 (0.47) | MAPTBDKRB1POLBKMT2AGAA | |
| SCHEMBL15372649 | 0.81 | BDKRB1 (0.47) | MAPTALDH1A1BDKRB1KDM4EKMT2A | |
| SCHEMBL14958727 | 0.78 | SMN1; SMN2 (0.45) | L3MBTL1MAPTALDH1A1BDKRB1KDM4E | |
| SCHEMBL12010118 | 0.77 | BDKRB1 (0.47) | BDKRB1POLBGAALMNAMAPK1 | |
| SCHEMBL3440525 | 0.77 | BDKRB1 (0.48) | MAPTBDKRB1POLBGAALMNA | |
| SCHEMBL12914508 | 0.76 | POLB (0.55) | MAPTBDKRB1POLBKMT2AGAA | |
| SCHEMBL3440009 | 0.75 | BDKRB1 (0.51) | MAPTBDKRB1POLBGAALMNA | |
| SCHEMBL3440280 | 0.75 | BDKRB1 (0.51) | MAPTBDKRB1POLBGAALMNA | |
| SCHEMBL3440282 | 0.74 | BDKRB1 (0.53) | MAPTBDKRB1POLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |