Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440208 | 0.89 | BDKRB1 (0.54) | ALDH1A1KDM4EBDKRB1KMT2AMAPT | |
| SCHEMBL15372649 | 0.83 | BDKRB1 (0.47) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL3440537 | 0.82 | BDKRB1 (0.59) | NPC1RAB9ABDKRB1GAAMAPK1 | |
| SCHEMBL14958754 | 0.82 | MAPT (0.54) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL10118727 | 0.80 | BDKRB1 (0.59) | BDKRB1KMT2AMAPTMEN1GFER | |
| SCHEMBL3439589 | 0.79 | BDKRB1 (0.49) | ALDH1A1KDM4EBDKRB1KMT2AMAPT | |
| SCHEMBL14958780 | 0.79 | BDKRB1 (0.60) | BDKRB1KMT2AGFERHRH3 | |
| SCHEMBL3440434 | 0.79 | BDKRB1 (0.54) | BDKRB1KMT2AMEN1 | |
| SCHEMBL3440299 | 0.78 | L3MBTL1 (0.39) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL12914508 | 0.78 | POLB (0.55) | SMN1; SMN2NPC1RAB9ABDKRB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |