Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760692 | 0.87 | ESR1 (0.60) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL1815385 | 0.83 | ESR1 (0.67) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL17431967 | 0.83 | ESR1 (0.56) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL12917725 | 0.83 | ESR1 (0.56) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL2246071 | 0.83 | ESR1 (0.60) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL38659424 | 0.82 | ESR1 (0.70) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL28226426 | 0.82 | ESR1 (0.70) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL29557461 | 0.81 | ESR1 (0.74) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL2862424 | 0.81 | ESR1 (0.74) | ESR1ESR2HSD17B1HSD17B2FGFR1 | |
| SCHEMBL7858240 | 0.81 | ESR1 (0.69) | ESR1ESR2HSD17B1HSD17B2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065361-B1 | Polymerisable compounds | MERCK PATENT GMBH (DE) | 2014-12-17 | — | — | EP | claimed |
| US-7807068-B2 | reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | claimed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | claimed |
| EP-2065361-A2 | Polymerisable compounds | Merck Patent GmbH (DE) | 2009-06-03 | — | — | EP | claimed |
| WO-2015115589-A1 | HALOGEN ATOM-SUBSTITUTED POLYMERIZABLE COMPOUND | 日産化学工業株式会社 | 2015-08-06 | — | — | WO | disclosed |
| EP-2065361-B1 | Polymerisable compounds | MERCK PATENT GMBH (DE) | 2014-12-17 | — | — | EP | disclosed |
| EP-2065361-B1 | Polymerisable compounds | MERCK PATENT GMBH (DE) | 2014-12-17 | — | — | EP | disclosed |
| US-7807068-B2 | reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |
| US-7807068-B2 | reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |
| US-7807068-B2 | reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | disclosed |
| EP-2065361-A2 | Polymerisable compounds | Merck Patent GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065361-A2 | Polymerisable compounds | Merck Patent GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | VCL, LCP1, LPXN | ESR1 606/4885ESR2 2083/4885RPS6KA3 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.