SCHEMBL3440742

SCHEMBL3440742

CN(C(=O)O)c1cccc2ccc(O)cc12

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.68
PTPN1 P18031 6/20 0.54
TRPV1 Q8NER1 8/20 0.51
SIGMAR1 Q99720 2/20 0.45
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25969106 0.82 MCL1 (0.65) MCL1PTPN1TRPV1MTNR1AMTNR1B
SCHEMBL6581360 0.82 MCL1 (0.60) MCL1PTPN1TRPV1SIGMAR1MTNR1A
Hydrochloric Acid SCHEMBL11015680 0.82 MCL1 (0.60) MCL1PTPN1TRPV1SIGMAR1MTNR1A
SCHEMBL1614544 0.81 SIGMAR1 (0.67) SIGMAR1
SCHEMBL29349880 0.81 MCL1 (1.00) MCL1PTPN1TRPV1SIGMAR1MTNR1A
SCHEMBL29666490 0.81 SIGMAR1 (0.67) SIGMAR1
SCHEMBL206372 0.80 MCL1 (0.58) MCL1PTPN1TRPV1MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL6432796 0.80 MCL1 (0.57) MCL1PTPN1TRPV1SIGMAR1MTNR1A
Hydrochloric Acid SCHEMBL7638732 0.80 MCL1 (0.57) MCL1PTPN1TRPV1SIGMAR1MTNR1A
SCHEMBL7341583 0.79 PLAU (0.53) MCL1PTPN1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010054760-A1 POLYURETHANE DISPERSIONS FOR COATINGS HAVING BARRIER PROPERTIES BAYER MATERIALSCIENCE AG (DE) 2010-05-20 WO disclosed
EP-2186839-A1 Polyurethane dispersions for coating with barrier features Bayer MaterialScience AG (DE) 2010-05-19 EP disclosed