SCHEMBL3440907

SCHEMBL3440907

C=CC(=O)OCCCC(C)C(C)(C)O[SiH3]

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.49
ALDH1A1 P00352 4/20 0.49
CYP3A4 P08684 2/20 0.49
HPGD P15428 1/20 0.49
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
HSD17B10 Q99714 1/20 0.41
THRB P10828 2/20 0.39
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31267565 0.86 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL236553 0.81 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29257289 0.79 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7525915 0.78 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL650621 0.77 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1017092 0.75 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27987243 0.75 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8899037 0.75 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
Propene SCHEMBL28139307 0.75 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14352187 0.75 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050244658-A1 Inorganic/organic hybrid oligomer and nano hybrid polymer for use in optical devices and displays, and process for preparing the same KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-11-03 US claimed
US-8299185-B2 Curable cage-type silicone copolymer and process for production thereof and curable resin composition comprising curable cage-type silicone copolymer and cured product thereof NIPPON STEEL CHEMICAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20100280190-A1 CURABLE CAGE-TYPE SILICONE COPOLYMER AND PROCESS FOR PRODUCTION THEREOF AND CURABLE RESIN COMPOSITION COMPRISING CURABLE CAGE-TYPE SILICONE COPOLYMER AND CURED PRODUCT THEREOF NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2010-11-04 US disclosed
US-7813615-B2 Flexible film optical waveguide using organic-inorganic hybrid material and fabrication method thereof KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-10-12 US disclosed
US-20090052856-A1 Flexible Film Optical Waveguide Using Organic-Inorganic Hybrid Material and Fabrication Method Thereof KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-02-26 US disclosed
WO-2006112592-A1 FLEXIBLE FILM OPTICAL WAVEGUIDE USING ORGANIC-INORGANIC HYBRID MATERIAL AND FABRICATION METHOD THEREOF KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2006-10-26 WO disclosed
US-20050244658-A1 Inorganic/organic hybrid oligomer and nano hybrid polymer for use in optical devices and displays, and process for preparing the same KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-11-03 US disclosed