SCHEMBL3440952

SCHEMBL3440952

C=C(CC=Cc1ccccc1)C(=O)OCCOc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.51
PAM P19021 1/20 0.47
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
PPARA Q07869 3/20 0.45
NPC1 O15118 2/20 0.43
TSHR P16473 1/20 0.43
PKM P14618 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAOB P27338 1/20 0.41
NAAA Q02083 2/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL409074 0.85 PAM (0.51) PAMSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL9244122 0.81 PAM (0.54) PAMRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL455010 0.81 KDM4E (0.51) PAMTSHRMEN1KMT2AKDM4E
SCHEMBL3363421 0.81 SMN1; SMN2 (0.55) THRBRAB9ASMN1; SMN2PPARANPC1
SCHEMBL1792779 0.80 MEN1 (0.55) PAMRAB9ASMN1; SMN2NPC1MEN1
SCHEMBL3803971 0.80 PAM (0.46) PAMTSHRMEN1KMT2AKDM4E
SCHEMBL5608312 0.79 PAM (0.59) PAMSMN1; SMN2ALDH1A1MAOBLMNA
SCHEMBL7242327 0.79 TSHR (0.47) PAMRAB9ASMN1; SMN2NPC1TSHR
Methacrylic Acid SCHEMBL3145235 0.79 PAM (0.45) PAMMEN1KMT2AKDM4EMAOB
SCHEMBL9442161 0.79 TSHR (0.47) PAMRAB9ASMN1; SMN2NPC1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820359-B2 Heat-sensitive transfer image-receiving sheet and coating composition for forming heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2010-10-26 US disclosed
US-7807330-B2 Heat-sensitive transfer image-receiving sheet and coating composition for forming heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2010-10-05 US disclosed
US-20080090178-A1 HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET AND COATING COMPOSITION FOR FORMING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20080081765-A1 HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET AND COATING COMPOSITION FOR FORMING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed