Cinnamaldehyde

Cinnamaldehyde

SCHEMBL3441

O=C/C=C/c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
LMNA P02545 2/20 1.00
MAPK1 P28482 2/20 1.00
TRPA1 O75762 1/20 1.00
ALOX5 P09917 1/20 1.00
MAOB P27338 1/20 0.68
MAPT P10636 3/20 0.58
KDM4E B2RXH2 1/20 0.58
CDK4 P11802 3/20 0.56
CCND1 P24385 3/20 0.56
CCNB2 O95067 2/20 0.56
CDK1 P06493 2/20 0.56
CCNB1 P14635 2/20 0.56
CCNB3 Q8WWL7 2/20 0.56
CYP2A6 P11509 1/20 0.52
CMA1 P23946 1/20 0.50
HDAC3 O15379 2/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC7 Q8WUI4 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamic Aldehyde SCHEMBL1866630 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL28377500 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamic Aldehyde SCHEMBL159856 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL28377503 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL3442 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL2203965 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL25267814 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL18527027 0.97 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL11865695 0.97 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL23581140 0.97 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1TRPA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 79153 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144780-A1 COMPOSITION FOR ENHANCING ADRENOMEDULLIN GENE EXPRESSION HOUSE WELLNESS FOODS CORPORATION (JP) 2026-05-28 US claimed
EP-4748918-A1 METHOD FOR ADVANCED CONTROL OF BIOCATALYTIC PROCESSES Delft Advanced Biofuels B.V. (NL) 2026-05-27 EP claimed
EP-4746708-A1 VOC COMPOSITION AND MINERAL CARRIER THEREOF Agriodor (FR) 2026-05-27 EP claimed
EP-4746862-A2 ENHANCED DELIVERY EPINEPHRINE AND PRODRUG COMPOSITIONS Aquestive Therapeutics, Inc. (US) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122080460-A Preparation method of pectin-based film based on chestnut bud polyphenol nanoemulsion 2026-05-26 CN claimed
CN-122076432-A Catalyst for preparing cinnamyl alcohol by selective hydrogenation of cinnamyl aldehyde, preparation method and application thereof 2026-05-26 CN claimed
CN-121516937-B Long-acting controlled-release antibacterial deodorizing material for water treatment and preparation method thereof Xi'an Water Innovation Material Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122080068-A Mitochondria-targeted lonidamine and cinnamaldehyde coupled prodrug as well as preparation method and application thereof 2026-05-26 CN claimed
CN-116965448-B Natural food preservative composition and application thereof Jinjiang Licheng Food Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-3963618-A POLYVINYL ACETALS BABCOCK & WILCOX LIMITED (EN) 1976-06-15 US claimed
US-3960685-A Photosensitive resin composition containing pullulan or esters thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-01 US claimed
US-3957823-A METALLIZATION BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-05-18 US claimed
US-3954981-A Triazolocycloalkylhydrothiadiazine derivatives RICHARDSON-MERRELL INC. (US) 1976-05-04 US claimed
US-3953524-A Catalytic hydrogenation of alpha,beta-unsaturated aldehydes to alpha,beta-unsaturated alcohols HOFFMANN-LA ROCHE INC. (US) 1976-04-27 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed
US-3947570-A MOUTHWASH, LEMON OIL COLGATE-PALMOLIVE COMPANY (US) 1976-03-30 US claimed
US-3944679-A Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) 1976-03-16 US claimed
US-3933746-A Photopolymerizable polymers having anhydride-containing groups BALL CORPORATION (US) 1976-01-20 US claimed
US-3931195-A ANTIARRHYTHMIA, ANTISEROTONIN MEAD JOHNSON & COMPANY (US) 1976-01-06 US claimed