Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568958 | 0.82 | AAK1 (0.38) | KDM4CAAK1ALDH1A1ACACBKDM4E | |
| SCHEMBL27837097 | 0.81 | CYP19A1 (0.40) | GAAKDM4CALDH1A1LOXLOXL2 | |
| SCHEMBL25984978 | 0.81 | KDM4C (0.44) | KDM4CAAK1ALDH1A1ACACBNOS1 | |
| SCHEMBL2920954 | 0.81 | KDM4E (0.44) | GAAKDM4CAAK1ALDH1A1ACACB | |
| SCHEMBL22946357 | 0.78 | MEN1 (0.40) | GAAKDM4CALDH1A1ACACBKDM4E | |
| SCHEMBL9573013 | 0.78 | KDM4E (0.36) | KDM4CAAK1ALDH1A1ACACBKDM4E | |
| SCHEMBL22557503 | 0.77 | ESR1 (0.39) | KDM4CLOXLOXL2NOS3NOS1 | |
| SCHEMBL7871639 | 0.77 | AAK1 (0.35) | KDM4CAAK1ALDH1A1ACACBKDM4E | |
| SCHEMBL22952872 | 0.76 | SMN1; SMN2 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL9018039 | 0.75 | KDM4E (0.44) | ALDH1A1ACACBKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133312-A1 | HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | WO | disclosed |
| EP-2253617-A1 | Halogenated compounds as pesticides | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-1202988-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| EP-1173468-A1 | INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2001010847-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |
| WO-2000066618-A1 | INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-09 | — | — | WO | disclosed |