Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573013 | 0.92 | KDM4E (0.36) | AAK1CCR1CCR5CCR8RIOK2 | |
| SCHEMBL7871639 | 0.90 | AAK1 (0.35) | AAK1CCR1CCR5CCR8RIOK2 | |
| SCHEMBL19664383 | 0.85 | ACACB (0.36) | ACACBKMT2AALDH1A1MEN1 | |
| SCHEMBL9706059 | 0.84 | MEN1 (0.49) | ACACBHPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL2549948 | 0.84 | CCR1 (0.57) | CCR1CCR5CCR8RIOK2KDM4E | |
| SCHEMBL9662430 | 0.83 | LMNA (0.36) | AAK1HSD17B10KMT2AALDH1A1 | |
| SCHEMBL3441226 | 0.82 | GAA (0.39) | AAK1ACACBKDM4EKDM6BKDM5C | |
| SCHEMBL9706023 | 0.82 | LOXL2 (0.46) | HPGD | |
| SCHEMBL19664384 | 0.81 | KMT2A (0.45) | KDM4ENOS3NOS1NOS2KMT2A | |
| SCHEMBL9663046 | 0.81 | TSHR (0.38) | AAK1ACACBKDM4ENOS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861206-B1 | COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A BINDING POLYMER, METHOD THEREFOR, AND USE THEREOF FOR TREATING HAIR | OREAL (FR) | 2019-06-12 | — | — | EP | claimed |
| EP-2861205-B1 | COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. | OREAL (FR) | 2017-12-06 | — | — | EP | claimed |
| EP-0548883-A1 | Substituted pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-30 | — | — | EP | disclosed |
| EP-0541042-A1 | 2,4- and 2,5-pyridine-dicarboxylic acid derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |