SCHEMBL3444459

SCHEMBL3444459

C[SiH](C)c1ccc2c(c1C1=CC=CC1)[CH]c1ccccc1-2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15610000 0.84
SCHEMBL4576059 0.80
SCHEMBL312236 0.76
SCHEMBL5086259 0.74 ELANE (0.33)
SCHEMBL27492646 0.74
SCHEMBL27819545 0.73
SCHEMBL7894684 0.73
Hydrochloric Acid SCHEMBL218802 0.72
SCHEMBL27528065 0.71
SCHEMBL7149162 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2277928-B1 Shear thinning ethylene/alpha-olefin interpolymers and their preparation DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-21 EP disclosed
US-9045569-B2 Process of making modified metallocene catalyst, catalyst produced and use thereof W. R. GRACE & CO.-CONN. (US) 2015-06-02 US disclosed
EP-1392741-B1 PROCESS FOR PREPARING SUPPORTED TRANSITION METAL CATALYST SYSTEMS AND CATALYST SYSTEMS PREPARED THEREBY GRACE W R & CO (US) 2014-06-25 EP disclosed
US-20130289227-A1 PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF W.R. GRACE & CO.-CONN (US) 2013-10-31 US disclosed
EP-1242478-B1 METALLOCENE AND CONSTRAINED GEOMETRY CATALYST SYSTEMS EMPLOYING AGGLOMERATED METAL OXIDE/CLAY SUPPORT-ACTIVATOR AND METHOD OF THEIR PREPARATION GRACE W R & CO (US) 2012-12-05 EP disclosed
US-7750104-B2 E.g.., ethylene-ethylidenenorbornene-propylene terpolymer, characterized by a Processing Rheology Ratio of at least 8; the polymers do not include a traditional branch-inducing monomer such as norbornadiene; prepared without H2 using a constrained geometry complex catalyst and an activating cocatalyst Dow Global Technologie Inc. (US) 2010-07-06 US disclosed
US-7491672-B2 Chemically-modified supports and supported catalyst systems prepared therefrom INEOS EUROPE LIMITED (GB) 2009-02-17 US disclosed
US-20080051531-A1 GAS PHASE PROCESS FOR POLYMERS WITH GROUP 4 METAL COMPLEX CATALYST ADDITION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2008-02-28 US disclosed
US-20070203314-A1 E.g.., ethylene-ethylidenenorbornene-propylene terpolymer, characterized by a Processing Rheology Ratio of at least 8; the polymers do not include a traditional branch-inducing monomer such as norbornadiene; prepared without H2 using a constrained geometry complex catalyst and an activating cocatalyst DUPONT DOW ELASTOMERS, LLC 2007-08-30 US disclosed
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
WO-1997035893-A1 HIGHLY SOLUBLE OLEFIN POLYMERIZATION CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1997-10-02 WO disclosed
WO-1997035892-A1 SOLUTION POLYMERIZATION PROCESS WITH DISPERSED CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1997-10-02 WO disclosed
EP-0793679-A1 ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-09-10 EP disclosed
EP-0781299-A2 SILYLIUM CATIONIC POLYMERIZATION ACTIVATORS FOR METALLOCENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-07-02 EP disclosed
WO-1997019965-A1 MONO-OLEFIN/POLYENE INTERPOLYMERS, METHOD OF PREPARATION, COMPOSITIONS CONTAINING THE SAME, AND ARTICLES MADE THEREOF THE DOW CHEMICAL COMPANY (US) 1997-06-05 WO disclosed
WO-1997019959-A1 SUPPORTED CATALYST CONTAINING TETHERED CATION FORMING ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1997-06-05 WO disclosed
US-5625087-A Silylium cationic polymerization activators for metallocene complexes THE DOW CHEMICAL COMPANY (US) 1997-04-29 US disclosed
WO-1996016095-A1 ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-05-30 WO disclosed
WO-1996008519-A2 SILYLIUM CATIONIC POLYMERIZATION ACTIVATORS FOR METALLOCENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-03-21 WO disclosed
US-5464906-A Polymerization catalyst THE DOW CHEMICAL COMPANY (US) 1995-11-07 US disclosed