SCHEMBL5086259

SCHEMBL5086259

CCCCc1ccc2c(c1C1=CC=CC1)[CH]c1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.33
CTSG P08311 3/20 0.33
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085193 0.85 ELANE (0.31) ELANECTSG
SCHEMBL5085995 0.85
SCHEMBL15610000 0.80
SCHEMBL4576059 0.76
SCHEMBL217439 0.74 NR1H2 (0.36) ELANECTSGNR1H2NR1H3
SCHEMBL3444459 0.74
SCHEMBL1029658 0.74 NR1H2 (0.38) ELANECTSGNR1H2NR1H3
SCHEMBL9123731 0.73 NR1H2 (0.37) ELANECTSGNR1H2NR1H3
SCHEMBL215717 0.72 NR1H2 (0.42) ELANECTSGNR1H2NR1H3
SCHEMBL312236 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1283223-B1 Use of a mixture of two metallocene regioisomers as catalyst component for preparing bimodal isotactic polyolefins TOTAL PETROCHEMICALS RES FELUY (BE) 2008-04-09 EP disclosed
EP-1163278-B1 USE AND PRODUCTION OF POLYPROPYLENE TOTAL PETROCHEMICALS RES FELUY (BE) 2007-01-10 EP disclosed
US-20040249094-A1 Use and production of polypropylene ATOFINA RESEARCH, S.A. (BE) 2004-12-09 US disclosed
EP-1169356-B1 POLYOLEFIN PRODUCTION ATOFINA RES (BE) 2004-07-14 EP disclosed
CN-1152056-C Polyolefin production ���з����о���˾ 2004-06-02 CN disclosed
US-6727332-B2 SPECIFIC METALLOCENE CATALYSTS USED TO PREPARE PROPYLENE POLYMERS WITH LOW MELTING TEMPERATURE, HIGH CRYSTALLISATION TEMPERATURE AND HIGH TRANSPARENCY; HIGH SPEED SOLIDIFICATION FROM MELT ATOFINA RESEARCH S.A. (BE) 2004-04-27 US disclosed
EP-1283223-A2 Polyolefin production ATOFINA Research (BE) 2003-02-12 EP disclosed
US-6515086-B1 A process for preparing polyolefins having a monomer length of up to C10, which comprises first contacting: (1) a metallocene catalyst component for the preparation of a polyolefin which comprises an isotactic polyolefin or FINA RESEARCH, S.A. (BE) 2003-02-04 US disclosed
US-20020120080-A1 Use and production of polypropylene ATOFINA RESEARCH, S.A. (BE) 2002-08-29 US disclosed
EP-1031582-A1 Use and production of polypropylene FINA RESEARCH S.A. (BE) 2000-08-30 EP disclosed
EP-0881236-A1 Metallocene catalyst component for use in producing isotactic polyolefins FINA RESEARCH S.A. (BE) 1998-12-02 EP disclosed