SCHEMBL3444656

SCHEMBL3444656

O=C(c1ccc(Cl)cc1)c1ccccc1C(=O)c1ccc(Cl)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.84
AKR1C3 P42330 3/20 0.58
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
SRD5A2 P31213 1/20 0.58
MAPK1 P28482 1/20 0.58
ALDH1A1 P00352 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
CDC25B P30305 1/20 0.55
ATM Q13315 1/20 0.55
MAPT P10636 1/20 0.54
MEN1 O00255 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28451754 0.96 NR4A1 (0.85) NR4A1AKR1C3CES2CES1SRD5A2
SCHEMBL30114756 0.96 NR4A1 (0.85) NR4A1AKR1C3CES2CES1SRD5A2
SCHEMBL1247787 0.92 NR4A1 (1.00) NR4A1AKR1C3CES2CES1SRD5A2
SCHEMBL30884880 0.92 NR4A1 (1.00) NR4A1AKR1C3CES2CES1SRD5A2
SCHEMBL6299251 0.92 NR4A1 (0.72) NR4A1AKR1C3CES2CES1SRD5A2
SCHEMBL2175941 0.90 NR4A1 (0.70) NR4A1AKR1C3CES2CES1SRD5A2
SCHEMBL9495711 0.90 NR4A1 (0.70) NR4A1AKR1C3CES2CES1SRD5A2
SCHEMBL2991958 0.89 NR4A1 (0.69) NR4A1CES2CES1SRD5A2MAPK1
SCHEMBL29989484 0.89 NR4A1 (0.69) NR4A1CES2CES1SRD5A2MAPK1
SCHEMBL17713295 0.88 NR4A1 (0.68) NR4A1AKR1C3CES2CES1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110268003-B Curable compound 株式会社大赛璐 2022-08-09 CN disclosed
US-11021438-B2 Curable compound DAICEL CORPORATION (JP) 2021-06-01 US disclosed
US-20200079726-A1 CURABLE COMPOUND DAICEL CORPORATION (JP) 2020-03-12 US disclosed
CN-110462906-A Amberplex, its manufacturing method and the energy storage device including it KOLON INC 2019-11-15 CN disclosed
EP-3556793-A1 CURABLE COMPOUND Daicel Corporation (JP) 2019-10-23 EP disclosed
CN-107188790-A A kind of preparation method of 1,4 2 (4 hydroxyl benzoyl group) benzene monomers 沈阳化工大学 2017-09-22 CN disclosed
US-7816053-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2010-10-19 US disclosed
US-20060280991-A1 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2006-12-14 US disclosed
US-5378770-A Oligomerizing alkali metal sulfide and dihalobenzene; reacting with bis(halobenzoyl)benzene KUREHA KAGAKU KOGYO K.K. (JP) 1995-01-03 US disclosed
US-5378771-A Sulfiding dihalobenzene and bis(halobenzoyl)benzene in two steps to copolymerize poly(arylene thioetherketoneketones) KUREHA KAGAKU KOGYO K.K.K. (JP) 1995-01-03 US disclosed
US-5250636-A Poly(arylene thioether-ketone-ketone) copolymer and production process thereof KUREHA KAGAKU KOGYO K.K. (JP) 1993-10-05 US disclosed
US-5248743-A Polythioethers KUREHA KAGAKU KOGYO K.K. (JP) 1993-09-28 US disclosed
EP-0459621-A2 Poly(arylene thioether-ketone-ketone) copolymer and production process thereof KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-12-04 EP disclosed
EP-0435674-A2 High-heat-resistant, crystalline block copolymers and production process thereof KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-07-03 EP disclosed
EP-0389902-A1 Process for producing aromatic polyetherketones BAYER AG (DE) 1990-10-03 EP disclosed
EP-0374462-A2 Process for preparing high molecular weight optionally branched polyarylene sulfides BAYER AG (DE) 1990-06-27 EP disclosed
US-4835242-A Aryl ether ketones BASF AKTIENGESELLSCHAFT (DE) 1989-05-30 US disclosed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP disclosed
EP-0275037-A2 Aryl ether ketones BASF Aktiengesellschaft (DE) 1988-07-20 EP disclosed
US-4105635-A MANUFACTURE OF AROMATIC POLYMERS CONTAINING KETONE AND SULPHONE GROUPS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079726-A1 CURABLE COMPOUND CNOT1, CCNH, ASH2L NR4A1 1246/4885AKR1C3 1849/4885CES2 1943/4885
US-11021438-B2 Curable compound CNOT1, CCNH, ASH2L NR4A1 1246/4885AKR1C3 1849/4885CES2 1943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.