Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3444656 | 0.92 | NR4A1 (0.84) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30114756 | 0.88 | NR4A1 (0.85) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28451754 | 0.88 | NR4A1 (0.85) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31672209 | 0.85 | AKR1C3 (0.68) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL78316 | 0.85 | AKR1C3 (0.68) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9809151 | 0.85 | NR4A1 (0.58) | NR4A1CES2CES1SRD5A2MAPK1 | |
| Hydrochloric Acid SCHEMBL8166523 | 0.84 | NR4A1 (0.54) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30884880 | 0.84 | NR4A1 (1.00) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1247787 | 0.84 | NR4A1 (1.00) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2175941 | 0.82 | NR4A1 (0.70) | NR4A1ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10113021-B2 | Propylene random copolymer | BOREALIS AG (AT) | 2018-10-30 | — | — | US | disclosed |
| US-20170218104-A1 | PROPYLENE RANDOM COPOLYMER | BOREALIS AG (AT) | 2017-08-03 | — | — | US | disclosed |
| EP-2610272-B1 | Catalyst component | BOREALIS AG (AT) | 2017-05-10 | — | — | EP | disclosed |
| US-20140357816-A1 | PROPYLENE RANDOM COPOLYMER | BOREALIS AG (AT) | 2014-12-04 | — | — | US | disclosed |
| WO-2013098150-A1 | PROPYLENE RANDOM COPOLYMER | BOREALIS AG (AT) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013098138-A1 | CATALYST COMPONENT | BOREALIS AG (AT) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610274-A1 | Propylene random copolymer | Borealis AG (AT) | 2013-07-03 | — | — | EP | disclosed |
| EP-2610272-A1 | Catalyst component | Borealis AG (AT) | 2013-07-03 | — | — | EP | disclosed |
| US-6942966-B1 | libraries formed by permutations; combinatorial chemistry; drug screening | ISIS PHARMACEUTICALS, INC. (US) | 2005-09-13 | — | — | US | disclosed |
| US-6828427-B1 | Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same | ISIS PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | disclosed |
| WO-1999012034-A1 | AMINE COMPOUNDS AND COMBINATORIAL LIBRARIES COMPRISING SAME | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-11 | — | — | WO | disclosed |
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1998008813-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| EP-0825164-A2 | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0817787-A1 | NITROGENOUS MACROCYCLIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
| WO-1996030377-A1 | NITROGENOUS MACROCYCLIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |