SCHEMBL3445499

SCHEMBL3445499

C=Cc1ccccc1OCCCCCC.CC(C)(C)NC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
CHRM2 P08172 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADRA2A P08913 1/20 0.43
MAPT P10636 1/20 0.43
OPRK1 P41145 1/20 0.43
HTR2B P41595 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
PPARG P37231 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
ALDH1A1 P00352 2/20 0.39
HTT P42858 1/20 0.39
MCHR1 Q99705 1/20 0.38
TLR8 Q9NR97 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3444868 0.99 CYP1A2 (0.41) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL4362496 0.94 CYP1A2 (0.46) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL3445740 0.90 ALDH1A1 (0.40) KMT2AMEN1LMNAMAPTHTR2B
SCHEMBL28034835 0.89 KMT2A (0.51) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL2097272 0.89 KMT2A (0.51) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL7535277 0.89 KMT2A (0.51) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL28035375 0.89 KMT2A (0.51) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL7540395 0.89 KMT2A (0.51) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL5562266 0.89 KMT2A (0.51) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL28034837 0.89 KMT2A (0.51) KMT2AMEN1NR1I2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed