SCHEMBL3446223

SCHEMBL3446223

C=C(C)C(=O)O[Si](C)(OC(=O)C(=C)C)O[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 3/20 0.35
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5672798 0.95 ALDH1A1 (0.44) ALDH1A1TSHRTHRBTDP1
SCHEMBL29161121 0.85 ALDH1A1 (0.52) ALDH1A1TSHRTHRBTDP1
SCHEMBL2407879 0.81 ALDH1A1 (0.44) ALDH1A1TSHRTHRBTDP1
SCHEMBL993470 0.81 ALDH1A1 (0.44) ALDH1A1TSHRTHRBTDP1
SCHEMBL139709 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTHRBTDP1
SCHEMBL3446620 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTHRBTDP1
SCHEMBL9395891 0.79 ALDH1A1 (0.42) ALDH1A1TSHRTHRBTDP1
SCHEMBL9715045 0.79 ALDH1A1 (0.42) ALDH1A1TSHRTHRBTDP1
SCHEMBL2744465 0.78 TSHR (0.36) ALDH1A1TSHR
SCHEMBL2584395 0.78 ALDH1A1 (0.46) ALDH1A1TSHRTHRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7815835-B2 Rapid prototyping method and radiation-curable composition for use therein TECHNISCHE UNIVERSITAT WIEN (AT) 2010-10-19 US claimed
US-20090224438-A1 Rapid Prototyping Method and Radiation-Curable Composition for Use Therein TECHNISCHE UNIVERSITAT WIEN (AT) 2009-09-10 US claimed
EP-1907192-B1 RAPID-PROTOTYPING METHOD AND USE IN THE METHOD OF A RADIATION-HARDENABLE COMPOSITION UNIV WIEN TECH (AT) 2008-11-19 EP claimed
EP-1907192-A1 RAPID-PROTOTYPING METHOD AND RADIATION-HARDENABLE COMPOSITION OF APPLICATION THERETO Technische Universität Wien (AT) 2008-04-09 EP claimed
WO-2007002965-A1 RAPID-PROTOTYPING METHOD AND RADIATION-HARDENABLE COMPOSITION OF APPLICATION THERETO TECHNISCHE UNIVERSITÄT WIEN (AT) 2007-01-11 WO claimed
US-7815835-B2 Rapid prototyping method and radiation-curable composition for use therein TECHNISCHE UNIVERSITAT WIEN (AT) 2010-10-19 US disclosed
US-20090224438-A1 Rapid Prototyping Method and Radiation-Curable Composition for Use Therein TECHNISCHE UNIVERSITAT WIEN (AT) 2009-09-10 US disclosed
EP-1907192-B1 RAPID-PROTOTYPING METHOD AND USE IN THE METHOD OF A RADIATION-HARDENABLE COMPOSITION UNIV WIEN TECH (AT) 2008-11-19 EP disclosed
EP-1907192-A1 RAPID-PROTOTYPING METHOD AND RADIATION-HARDENABLE COMPOSITION OF APPLICATION THERETO Technische Universität Wien (AT) 2008-04-09 EP disclosed
WO-2007002965-A1 RAPID-PROTOTYPING METHOD AND RADIATION-HARDENABLE COMPOSITION OF APPLICATION THERETO TECHNISCHE UNIVERSITÄT WIEN (AT) 2007-01-11 WO disclosed