SCHEMBL34463085

SCHEMBL34463085

COc1ccc(F)c(/C=C/[N+](=O)[O-])c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.56
VCP P55072 7/20 0.51
FBP1 P09467 5/20 0.47
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
HTT P42858 2/20 0.44
SYK P43405 2/20 0.44
EGFR P00533 2/20 0.44
GALR2 O43603 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
PTGS2 P35354 1/20 0.41
MITF O75030 1/20 0.40
HSP90AA1 P07900 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34463103 0.89 PRMT1 (0.49) PRMT1VCPFBP1KMT2AALDH1A1
SCHEMBL6960287 0.86 VCP (0.53) PRMT1VCPFBP1KMT2AALDH1A1
SCHEMBL6954065 0.86 VCP (0.53) PRMT1VCPFBP1KMT2AALDH1A1
SCHEMBL21799239 0.82 PRMT1 (0.60) PRMT1VCPFBP1ALDH1A1LMNA
SCHEMBL21799238 0.82 PRMT1 (0.60) PRMT1VCPFBP1ALDH1A1LMNA
SCHEMBL34462745 0.80 PRMT1 (0.57) PRMT1VCPFBP1KMT2AALDH1A1
SCHEMBL4501433 0.76 PRMT1 (0.74) PRMT1VCPFBP1KMT2AALDH1A1
SCHEMBL14812451 0.76 PRMT1 (0.74) PRMT1VCPFBP1KMT2AALDH1A1
SCHEMBL4501431 0.76 PRMT1 (0.74) PRMT1VCPFBP1KMT2AALDH1A1
SCHEMBL453409 0.75 ERN1 (0.43) KMT2AALDH1A1TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed