Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272611 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL25311662 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL4271566 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL4270142 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL4270730 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL4269746 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL758110 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL4269442 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL4277904 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL10361006 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109796-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260110920-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2026-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260110920-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | ERCC1, ERCC5, ERCC4 | ALDH1A1 3021/4885TDP1 2953/4885CYP3A4 476/4885 |
| US-20260109796-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | ERCC1, PDE6H, HCK | ALDH1A1 2416/4885TDP1 3645/4885CYP3A4 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.