Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 16/20 | 0.54 |
| ▸ | JAK3 | P52333 | 10/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | JAK1 | P23458 | 5/20 | 0.54 |
| ▸ | TYK2 | P29597 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | OPA1 | O60313 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | STK16 | O75716 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34464824 | 0.92 | CAMK2D (0.48) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464869 | 0.91 | JAK2 (0.47) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464746 | 0.88 | JAK2 (0.67) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464802 | 0.87 | JAK2 (0.53) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464847 | 0.86 | JAK2 (0.45) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464777 | 0.86 | JAK2 (0.63) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464820 | 0.85 | JAK2 (0.54) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464769 | 0.84 | JAK2 (0.53) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464833 | 0.84 | JAK2 (0.53) | JAK2JAK3HDAC1JAK1TYK2 | |
| SCHEMBL34464818 | 0.84 | JAK2 (0.53) | JAK2JAK3HDAC1JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109690-A1 | HDAC6 INHIBITORS AND METHOD OF THEIR USE | BAERENKRAFT THERAPEUTICS LLC (US) | 2026-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109690-A1 | HDAC6 INHIBITORS AND METHOD OF THEIR USE | HDAC6, HDAC3, HDAC1 | JAK2 2639/4885JAK3 3362/4885HDAC1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.