⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34466556 | 0.89 | TSHR (0.30) | — | |
| SCHEMBL35212571 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL34466518 | 0.89 | ALDH1A1 (0.30) | — | |
| SCHEMBL35211848 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL35212379 | 0.83 | CCR1 (0.30) | — | |
| SCHEMBL35212427 | 0.83 | CCR1 (0.30) | — | |
| SCHEMBL34465723 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL34465835 | 0.83 | TSHR (0.30) | — | |
| SCHEMBL35212101 | 0.82 | — | — | |
| SCHEMBL35212626 | 0.81 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108509-A1 | 6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260109704-A1 | 5-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-04-23 | — | — | US | disclosed |