SCHEMBL34466431

SCHEMBL34466431

CN(c1ccc(OCCN)cc1)c1ccc(N2CCN(CC(=O)Nc3ccc4c(c3)CN([C@H]3CCC(=O)NC3=O)C4=O)CC2)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 15/20 0.48
▸ GSPT1 P15170 5/20 0.48
▸ IKZF3 Q9UKT9 2/20 0.48
▸ DDB1 Q16531 1/20 0.48
▸ CSNK1A1 P48729 7/20 0.46
▸ IKZF2 Q9UKS7 10/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34466147 0.93 CRBN (0.47) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34465797 0.93 CRBN (0.48) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34466104 0.93 CRBN (0.46) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34465968 0.89 CRBN (0.47) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34465520 0.88 CRBN (0.45) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34466463 0.88 CRBN (0.55) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34465626 0.88 CRBN (0.47) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34465715 0.88 CRBN (0.47) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34466160 0.88 CRBN (0.51) CRBNGSPT1IKZF3DDB1CSNK1A1
SCHEMBL34466650 0.87 CRBN (0.47) CRBNGSPT1IKZF3DDB1CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF GENOSCO INC (US) 2026-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF CRBN, PSMB3, PSMB1 CRBN 1/4885GSPT1 21/4885IKZF3 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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