Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.37 |
| ▸ | JAK1 | P23458 | 4/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31755992 | 0.86 | JAK2 (0.38) | JAK2JAK1IRAK4CHRNB2CHRNB4 | |
| SCHEMBL31756017 | 0.83 | JAK2 (0.43) | JAK2JAK1IRAK4CHRNB2CHRNB4 | |
| SCHEMBL31756438 | 0.83 | JAK2 (0.43) | JAK2JAK1IRAK4CHRNB2CHRNB4 | |
| SCHEMBL34467918 | 0.77 | JAK2 (0.39) | JAK2JAK1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL34468017 | 0.76 | JAK2 (0.38) | JAK2JAK1IRAK4CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL31756378 | 0.75 | CDK4 (0.44) | CDK1CDK2 | |
| SCHEMBL1991037 | 0.74 | CTSK (0.48) | CTSSCTSKCDK1CDK2 | |
| SCHEMBL31756023 | 0.74 | JAK2 (0.39) | JAK2JAK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL34467999 | 0.74 | JAK2 (0.39) | JAK2JAK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL31756293 | 0.74 | JAK2 (0.39) | JAK2JAK1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116888-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | NOVARTIS AG (CH) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116888-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK4, CCNC, CDK6 | JAK2 330/4885JAK1 358/4885IRAK4 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.