SCHEMBL34472779

SCHEMBL34472779

Nc1ccc(OCF)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.32
HTR2A P28223 3/20 0.32
HTR2C P28335 3/20 0.32
HTR2B P41595 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
DRD1 P21728 1/20 0.31
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34473075 0.83 HTR2C (0.35) KDM4EMAPTCRHBPCRHR2HTR2A
SCHEMBL7736641 0.83 MAPT (0.53) KDM4EMAPTALDH1A1HSD17B10MEN1
SCHEMBL34472389 0.82 HTR2A (0.34) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL18135159 0.82 KDM4E (0.33) KDM4EMAPTCRHBPCRHR2
SCHEMBL34472182 0.82 KDM4E (0.33) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL34473377 0.82 KDM4E (0.33) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL34472485 0.79 MAPT (0.35) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL34472930 0.79 KDM4E (0.32) KDM4EMAPTCRHBPCRHR2
SCHEMBL34473443 0.79 KDM4E (0.32) KDM4EMAPTCRHBPCRHR2
SCHEMBL34472249 0.79 HTR2A (0.34) KDM4EMAPTCRHBPCRHR2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed