SCHEMBL7736641

SCHEMBL7736641

CCOc1ccc(N)c(F)c1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
ALDH1A1 P00352 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
POLB P06746 2/20 0.53
HPGD P15428 1/20 0.53
MAPK1 P28482 1/20 0.53
NPC1 O15118 2/20 0.46
USP2 O75604 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CREBBP Q92793 1/20 0.44
GAA P10253 1/20 0.44
TDP1 Q9NUW8 3/20 0.41
KDM1A O60341 2/20 0.41
PDE4A P27815 2/20 0.40
PDE4B Q07343 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17527769 0.86 L3MBTL1 (0.48) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL10909552 0.86 ALDH1A1 (0.48) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL5205296 0.83 ALDH1A1 (0.64) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL34472779 0.83 KDM4E (0.36) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL9405807 0.81 CYP1A2 (0.47) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL20226538 0.81 CYP1A2 (0.47) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL4405598 0.81 ALDH1A1 (0.45) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL1429875 0.77 IDO1 (0.48) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL24240291 0.77 L3MBTL1 (0.47) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E
SCHEMBL16855852 0.77 L3MBTL1 (0.42) MAPTL3MBTL1ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402041-B Synthesis method of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2025-01-14 CN claimed
CN-117402041-A Synthesis method of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2024-01-16 CN claimed
CN-117402041-B Synthesis method of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2025-01-14 CN disclosed
CN-117402041-B Synthesis method of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2025-01-14 CN disclosed
CN-117599687-A Synthesis device of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2024-02-27 CN disclosed
CN-117599687-A Synthesis device of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2024-02-27 CN disclosed
CN-117402041-A Synthesis method of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2024-01-16 CN disclosed
CN-117402041-A Synthesis method of 4-ethoxy-2, 3-difluorophenol 浙江吉泰新材料股份有限公司 2024-01-16 CN disclosed
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 US disclosed
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2021-02-11 US disclosed
US-10711032-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2020-07-14 US disclosed
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2018-06-07 US disclosed
US-9783539-B2 Indoloquinolone compounds as anaplastic lymphoma kinase (ALK) inhibitors JIANGSU ASCENTAGE BIOMED DEVELOPMENT INC. (CN) 2017-10-10 US disclosed
US-20170066761-A1 INDOLOQUINOLONE COMPOUNDS AS ANAPLASTIC LYMPHOMA KINASE (ALK) INHIBITORS JIANGSU ASCENTAGE BIOMED DEVELOPMENT INC. (CN) 2017-03-09 US disclosed
EP-3110815-A1 INDOLOQUINOLONE COMPOUNDS AS ANAPLASTIC LYMPHOMA KINASE (ALK) INHIBITORS Jiangsu Ascentage Biomed Development Inc. (CN) 2017-01-04 EP disclosed
WO-2015127629-A1 INDOLOQUINOLONE COMPOUNDS AS ANAPLASTIC LYMPHOMA KINASE (ALK) INHIBITORS JIANGSU ASCENTAGE BIOMED DEVELOPMENT INC. (CN) 2015-09-03 WO disclosed
US-20150011528-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OF ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME YUHAN CORPORATION (KR) 2015-01-08 US disclosed
EP-2758384-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Yuhan Corporation (KR) 2014-07-30 EP disclosed
WO-2013043001-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME YUHAN CORPORATION (KR) 2013-03-28 WO disclosed
US-6403172-B1 6-HEXYLOXY-3-FLUORO-2-(4-HEXYLPHENYL) BENZO(B)THIOPHENE AS FERROELECTRIC SWITCHES OR DISPLAYING DEVICES; DIELECTRIC ANISOTROPY CLARIANT INTERNATIONAL LTD. (CH) 2002-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170066761-A1 INDOLOQUINOLONE COMPOUNDS AS ANAPLASTIC LYMPHOMA KINASE (ALK) INHIBITORS ALK, BCL6, BCL6B MAPT 1973/4885L3MBTL1 3986/4885ALDH1A1 821/4885
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 MAPT 3285/4885L3MBTL1 2840/4885ALDH1A1 4143/4885
US-20150011528-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OF ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ILK, PKMYT1, PLAUR MAPT 813/4885L3MBTL1 1631/4885ALDH1A1 3792/4885
US-10711032-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 MAPT 3285/4885L3MBTL1 2840/4885ALDH1A1 4143/4885
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 MAPT 2999/4885L3MBTL1 2855/4885ALDH1A1 4113/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 MAPT 2999/4885L3MBTL1 2855/4885ALDH1A1 4113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.