SCHEMBL34472783

SCHEMBL34472783

Cc1nc(N)c(N)nc1C

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
IDO1 P14902 4/20 0.39
NQO1 P15559 1/20 0.39
NOS1 P29475 4/20 0.38
NOS3 P29474 3/20 0.36
NOS2 P35228 3/20 0.36
MAPT P10636 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
ADRA2A P08913 1/20 0.30
ADORA2A P29274 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11836648 1.00 LMNA (0.58) LMNAALDH1A1KDM4EIDO1NQO1
SCHEMBL7267205 0.85 LMNA (0.46) LMNAALDH1A1KDM4EIDO1NOS1
SCHEMBL2643813 0.83 LMNA (0.50) LMNAALDH1A1KDM4EIDO1NQO1
SCHEMBL5925893 0.77 LMNA (0.40) LMNAALDH1A1KDM4EIDO1NOS1
SCHEMBL7267204 0.77 LMNA (0.40) LMNAALDH1A1KDM4EIDO1NOS1
SCHEMBL6038800 0.77 LMNA (0.52) LMNAALDH1A1KDM4EIDO1NOS1
SCHEMBL13165396 0.77 LMNA (0.40) LMNAALDH1A1KDM4EIDO1NOS1
SCHEMBL8663843 0.75 LMNA (1.00) LMNAALDH1A1KDM4EIDO1GAA
SCHEMBL31128244 0.75 LMNA (0.71) LMNAALDH1A1KDM4EIDO1HSD17B10
SCHEMBL9557360 0.73 LMNA (0.37) LMNAALDH1A1KDM4EIDO1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026088070-A1 COMPOUNDS PFIZER INC. (US) 2026-04-30 WO disclosed