Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089899 | 0.90 | NR1H2 (0.41) | NR1H2MAPK1DDB1CRBNUSP2 | |
| SCHEMBL26136524 | 0.77 | NR1H2 (0.38) | NR1H2USP30MAPK1DDB1CRBN | |
| SCHEMBL26103366 | 0.76 | CRBN (0.40) | NR1H2MAPK1DDB1CRBNACACB | |
| SCHEMBL19032234 | 0.75 | CYP11B2 (0.45) | USP30DDB1CRBNCYP11B2ACACB | |
| SCHEMBL31649152 | 0.74 | USP2 (0.41) | NR1H2USP30IMPDH2CYP11B2ACACB | |
| SCHEMBL30761073 | 0.74 | MAPK1 (0.40) | NR1H2MAPK1DDB1CRBNUSP2 | |
| SCHEMBL12544852 | 0.73 | USP30 (0.45) | NR1H2USP30MAPK1DDB1CRBN | |
| SCHEMBL29392706 | 0.73 | USP30 (0.40) | NR1H2USP30MAPK1DDB1CRBN | |
| SCHEMBL29622412 | 0.73 | USP2 (0.46) | NR1H2CYP11B2ACACBUSP2SMN1; SMN2 | |
| SCHEMBL21658756 | 0.72 | USP2 (0.38) | NR1H2USP30MAPK1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026085629-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2026-04-30 | — | — | WO | disclosed |