Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447114 | 0.92 | GRM5 (0.46) | ESR1NPC1RAB9ANR1H3SCN2A | |
| SCHEMBL13433467 | 0.92 | GRM5 (0.46) | ESR1NPC1RAB9ANR1H3SCN2A | |
| SCHEMBL2624624 | 0.90 | ESR1 (0.43) | ESR1NPC1RAB9ANR1H3SCN2A | |
| SCHEMBL10352333 | 0.90 | NR1H3 (0.53) | ESR1NPC1RAB9ANR1H3SCN2A | |
| SCHEMBL14806847 | 0.88 | MAPK1 (0.49) | ESR1NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL13433469 | 0.85 | ESR1 (0.42) | ESR1NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL13433473 | 0.85 | ESR1 (0.42) | ESR1NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL22580699 | 0.84 | HSD17B10 (0.60) | RAB9AMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29857329 | 0.84 | HSD17B10 (0.60) | RAB9AMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11201186 | 0.84 | BRD4 (0.56) | ESR1NPC1RAB9AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100059261-A1 | REACTIVE MONOMER AND RESIN COMPOSITION CONTAINING SAME | AMT LABORATORY CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100059261-A1 | REACTIVE MONOMER AND RESIN COMPOSITION CONTAINING SAME | RAD51, ACTR2, ARID2 | ESR1 231/4885NPC1 4668/4885RAB9A 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.