Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL149204 | 1.00 | CA4 (0.60) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL29764190 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5163319 | 0.94 | CA4 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL16341496 | 0.94 | CA4 (0.55) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL28420909 | 0.94 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL1332143 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2351948 | 0.94 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL2275798 | 0.94 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL852 | 0.94 | — | — | |
| Bicarbonate SCHEMBL97148 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116333652-A | Waterproof glue for leather shoes and preparation method thereof | 浙江佰纳鞋业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2013015608-A2 | ZIRCONIUM ALLOY ELECTROPLATING SOLUTION COMPOSITION AND PLATED PRODUCT USING THE SAME | YOON JONG-OH (KR) | 2013-01-31 | — | — | WO | disclosed |
| WO-2010062624-A2 | ADHESIVE COMPOSITIONS FOR HYDROPHOBIC PHOTOPOLYMERS | ZEBRA IMAGING, INC. (US) | 2010-06-03 | — | — | WO | disclosed |
| US-20100104862-A1 | Adhesive Compositions for Hydrophobic Photopolymers | ZEBRA IMAGING, INC. (US) | 2010-04-29 | — | — | US | disclosed |