SCHEMBL3450428

SCHEMBL3450428

CCN(CC)c1ccc2c(c1)Sc1cc(N(CC)CC)ccc1N2C(=O)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.74
KMT2A Q03164 2/20 0.74
L3MBTL1 Q9Y468 2/20 0.74
MAPK1 P28482 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
BCHE P06276 13/20 0.56
ACHE P22303 5/20 0.56
SLC6A3 Q01959 1/20 0.48
HPGD P15428 1/20 0.45
POLB P06746 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 1/20 0.43
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009237 0.95 MEN1 (0.83) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL9009040 0.90 MEN1 (0.64) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL9009191 0.88 MEN1 (0.57) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL27923887 0.88 MEN1 (0.67) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL11314184 0.87 MEN1 (0.56) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL14476957 0.85 MAPK1 (0.83) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL388483 0.85 MEN1 (1.00) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL29406737 0.85 MEN1 (1.00) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL10788856 0.83 MEN1 (0.55) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL29850616 0.82 NOX1 (0.50) MEN1KMT2AL3MBTL1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030139293-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2003-07-24 US claimed
EP-1268215-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2003-01-02 EP claimed
WO-2001072527-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-10-04 WO claimed
EP-1316582-B1 POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES KURARAY CO (JP) 2012-10-31 EP disclosed
US-7820261-B2 Polyvinyl alcohol resin composition and multilayer packages KURARAY CO., LTD. (JP) 2010-10-26 US disclosed
US-20070243351-A1 POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES KURARAY CO. LTD. (JP) 2007-10-18 US disclosed
US-7255904-B2 Polyvinyl alcohol resin composition and multilayer packages KURARAY CO., LTD. (JP) 2007-08-14 US disclosed
US-20030139293-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2003-07-24 US disclosed
US-6586364-B2 Shell walls; liquid coloring PENTAX CORPORATION (JP) 2003-07-01 US disclosed
EP-1316582-A1 POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES KURARAY CO., LTD. (JP) 2003-06-04 EP disclosed
EP-0845708-B1 PLATE FOR WATERLESS LITHOGRAPHY TORAY INDUSTRIES (JP) 2003-02-12 EP disclosed
US-5565402-A RECORDING LAYER CONTAINING BLACK-FORMING FLUORAN DERIVATIVE AS BASIC DYE, PHENOTHIAZINE DERIVATIVE, DIPHENYL SULFONE DERIVATIVE COLOR ACCEPTOR NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0245505-B2 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER ASAHI CHEMICAL IND (JP) 1996-08-14 EP disclosed
EP-0434469-B1 Hydrogenation catalyst composition and process for hydrogenating olefinically unsaturated polymer using the same JAPAN SYNTHETIC RUBBER CO LTD (JP) 1995-02-22 EP disclosed
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 US disclosed
US-5169905-A Using a bis(cyclopentadienyl)transition metal compound and an alkali aluminum organic complex as catalyst JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-08 US disclosed
US-5115035-A Modified block copolymer of conjugated diene and vinylaromatic and a tackifier resin ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-05-19 US disclosed
EP-0434469-A2 Hydrogenation catalyst composition and process for hydrogenating olefinically unsaturated polymer using the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-06-26 EP disclosed
US-5011634-A Microcapsules and microcapsule production process PAPIERFABRIK AUGUST KOEHLER AG (DE) 1991-04-30 US disclosed
EP-0245505-A1 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-19 EP disclosed