SCHEMBL9009237

SCHEMBL9009237

CCN(CC)c1ccc2c(c1)Sc1cc(N(C)C)ccc1N2C(=O)c1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.83
KMT2A Q03164 2/20 0.83
L3MBTL1 Q9Y468 2/20 0.83
MAPK1 P28482 2/20 0.83
TDP1 Q9NUW8 1/20 0.83
BCHE P06276 12/20 0.51
ACHE P22303 4/20 0.51
SLC6A3 Q01959 1/20 0.44
HPGD P15428 1/20 0.42
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.41
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.40
SNCA P37840 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3450428 0.95 MEN1 (0.74) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL29406737 0.91 MEN1 (1.00) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL388483 0.91 MEN1 (1.00) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL14476957 0.91 MAPK1 (0.83) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL11143818 0.86 MEN1 (0.90) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL9009040 0.86 MEN1 (0.64) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL13019550 0.85 MEN1 (0.88) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL9009191 0.84 MEN1 (0.57) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL11595006 0.84 MAPK1 (0.56) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL27923887 0.83 MEN1 (0.67) MEN1KMT2AL3MBTL1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565402-A RECORDING LAYER CONTAINING BLACK-FORMING FLUORAN DERIVATIVE AS BASIC DYE, PHENOTHIAZINE DERIVATIVE, DIPHENYL SULFONE DERIVATIVE COLOR ACCEPTOR NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed