Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | GMPS | P49915 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 2/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711083 | 0.95 | ADORA3 (0.45) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL10712341 | 0.95 | ADORA3 (0.44) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL10709847 | 0.93 | ADORA3 (0.43) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL10707529 | 0.92 | ADORA3 (0.47) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL5180925 | 0.92 | ADORA3 (0.46) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL10709090 | 0.92 | SLC28A2 (0.43) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL10707448 | 0.92 | ADORA3 (0.42) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL11016801 | 0.92 | ADORA3 (0.46) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL10599784 | 0.91 | GMPS (0.45) | ADORA3POLBADORA2AGMPSPI4KA | |
| SCHEMBL10709861 | 0.90 | ADORA3 (0.46) | ADORA3POLBADORA2AGMPSPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181129-B1 | N6-SUBSTITUTED DEOXYRIBOSE ANALOGS OF ADENOSINES | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | claimed |
| EP-0139358-B1 | N6-SUBSTITUTED DIARYLALKYL ADENOSINES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | WARNER-LAMBERT COMPANY (US) | 1988-11-09 | — | — | EP | claimed |
| EP-0181129-A2 | N6-substituted deoxyribose analogs of adenosines | WARNER-LAMBERT COMPANY (US) | 1986-05-14 | — | — | EP | claimed |
| EP-0175465-A1 | An association of, or composition comprising, haloperidol and a diphenylalkyl adenosine or a diphenylalkyl-2-amino adenosine | WARNER-LAMBERT COMPANY (US) | 1986-03-26 | — | — | EP | claimed |
| EP-0139358-A2 | N6-substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1985-05-02 | — | — | EP | claimed |
| US-10675278-B2 | Crush resistant delayed-release dosage forms | Grünenthal GmbH (DE) | 2020-06-09 | — | — | US | disclosed |
| US-20180369235-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2018-12-27 | — | — | US | disclosed |
| US-20170312271-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2017-11-02 | — | — | US | disclosed |
| EP-2478896-B1 | Fracture-resistant application forms with delayed release | GRUENENTHAL GMBH (DE) | 2017-09-06 | — | — | EP | disclosed |
| EP-1845956-B1 | BREAK-RESISTANT DELAYED-RELEASE FORMS OF ADMINISTRATION | GRUENENTHAL GMBH (DE) | 2017-03-22 | — | — | EP | disclosed |
| US-20160184297-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160120810-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-05-05 | — | — | US | disclosed |
| EP-1019427-A1 | N?6 -SUBSTITUTED-ADENOSINE-5'-URONAMIDES AS ADENOSINE RECEPTOR MODULATORS | Medco Research, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999006053-A1 | N6-SUBSTITUTED-ADENOSINE-5'-URONAMIDES AS ADENOSINE RECEPTOR MODULATORS | MEDCO RESEARCH, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1996002553-A2 | AMINO PURINE-β-D-RIBOFURANURONAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1996-02-01 | — | — | WO | disclosed |
| EP-0181129-B1 | N6-SUBSTITUTED DEOXYRIBOSE ANALOGS OF ADENOSINES | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |
| EP-0139358-B1 | N6-SUBSTITUTED DIARYLALKYL ADENOSINES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | WARNER-LAMBERT COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0181129-A2 | N6-substituted deoxyribose analogs of adenosines | WARNER-LAMBERT COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |
| EP-0175465-A1 | An association of, or composition comprising, haloperidol and a diphenylalkyl adenosine or a diphenylalkyl-2-amino adenosine | WARNER-LAMBERT COMPANY (US) | 1986-03-26 | — | — | EP | disclosed |
| EP-0139358-A2 | N6-substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |