Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 14/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34495 | 0.98 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Hydrochloric Acid SCHEMBL35021 | 0.97 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Sulfuric Acid SCHEMBL12544525 | 0.94 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL16934856 | 0.93 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL34897 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL34670 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Hydrochloric Acid SCHEMBL18260148 | 0.92 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL34858 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL34601 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Trifluoromethanesulfonic Acid SCHEMBL34312 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473277-B1 | PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION OR ACID-FUNCTIONALIZED IONIC LIQUID | UNIV DENMARK TECH DTU (DK) | 2019-07-03 | — | — | EP | disclosed |
| US-20170341067-A1 | Palladium Catalyst System Comprising Zwitterion And/Or Acid-Functionalyzed Ionic Liquid | UNIV DENMARK TECH DTU (DK) | 2017-11-30 | — | — | US | disclosed |
| EP-2473277-A1 | PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALIZED IONIC LIQUID | Technical University of Denmark (DK) | 2012-07-11 | — | — | EP | disclosed |
| US-20110065950-A1 | PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALYZED IONIC LIQUID | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2011-03-17 | — | — | US | disclosed |
| WO-2011026860-A1 | PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALIZED IONIC LIQUID | TECHNICAL UNIVERISTY OF DENMARK (DK) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065950-A1 | PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALYZED IONIC LIQUID | PDCD2L, PCCA, PDK2 | SMN1; SMN2 2392/4885MEN1 1283/4885HSP90AA1 4752/4885 |
| US-20170341067-A1 | Palladium Catalyst System Comprising Zwitterion And/Or Acid-Functionalyzed Ionic Liquid | PDCD2L, PCCA, PDK2 | SMN1; SMN2 2392/4885MEN1 1283/4885HSP90AA1 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.