Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.41 |
| ▸ | MEN1 | O00255 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109550 | 0.99 | KMT2A (0.41) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL13109555 | 0.99 | KMT2A (0.41) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL3452102 | 0.91 | KMT2A (0.39) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL3452106 | 0.91 | KMT2A (0.39) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL3452619 | 0.91 | KMT2A (0.39) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL3451223 | 0.86 | ITGB3 (0.45) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL13109546 | 0.85 | ITGB3 (0.46) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL3451457 | 0.85 | ITGB3 (0.47) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL3451932 | 0.84 | ITGB3 (0.47) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL3451936 | 0.84 | ITGB3 (0.47) | KMT2AMEN1ALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | MC5R, MC3R, MC4R | KMT2A 2090/4885MEN1 1990/4885ALDH1A1 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.