Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051018 | 1.00 | NOS2 (0.39) | NOS2GAAMAPTPLAUALOX15 | |
| Bromide SCHEMBL7993026 | 0.98 | NOS2 (0.38) | NOS2GAAMAPTPLAU | |
| SCHEMBL3541131 | 0.98 | NOS2 (0.38) | NOS2GAAMAPTPLAU | |
| SCHEMBL5471703 | 0.78 | NISCH (0.35) | GAAMAPT | |
| SCHEMBL27741572 | 0.77 | — | — | |
| SCHEMBL11397499 | 0.75 | GAA (0.39) | GAAMAPT | |
| SCHEMBL11397495 | 0.75 | GAA (0.39) | GAAMAPT | |
| SCHEMBL2516589 | 0.74 | PLAU (0.35) | GAAMAPTPLAU | |
| SCHEMBL18321326 | 0.72 | NISCH (0.34) | GAA | |
| SCHEMBL1384491 | 0.72 | GAA (0.32) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2927 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798172-A | Preparation method of Leitemivir key intermediate dihydroquinazoline ester | 仁合益康集团有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-115819170-B | Method for synthesizing chiral dihydroquinazoline compound | 山西警察学院 | 2024-06-21 | — | — | CN | claimed |
| US-RE49897-E1 | Salts of a dihydroquinazoline derivative | AIC246 AG & CO. KG (DE) | 2024-04-02 | — | — | US | claimed |
| EP-4244210-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | Inipharm, Inc. (US) | 2023-09-20 | — | — | EP | claimed |
| CN-116670118-A | Dichlorophenol HSD17B13 inhibitor and application thereof | 伊尼制药公司 | 2023-08-29 | — | — | CN | claimed |
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | claimed |
| CN-116005178-B | Synthesis method of 1,2-dihydro quinazoline compound | 淮北师范大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116005178-A | Synthesis method of 1,2-dihydro quinazoline compound | 淮北师范大学 | 2023-04-25 | — | — | CN | claimed |
| CN-115947694-A | Preparation method of dihydroquinazoline compound | 云南大学 | 2023-04-11 | — | — | CN | claimed |
| EP-3421454-B1 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-04-05 | — | — | EP | claimed |
| WO-2003000181-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO., INC. (US) | 2003-01-03 | — | — | WO | claimed |
| JP-2002537391-A | — | — | 2002-11-05 | — | — | JP | claimed |
| WO-2002083884-A2 | IMMOBILIZING METHOD AND ARRANGEMENTS OF COMPOUNDS, WHICH ARE PRODUCED THEREWITH, ON A PLANAR SURFACE | JERINI AG (DE) | 2002-10-24 | — | — | WO | claimed |
| EP-1155012-A1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | Cancer Research Ventures Limited (GB) | 2001-11-21 | — | — | EP | claimed |
| WO-2000050417-A1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | CANCER RESEARCH VENTURES LIMITED (GB) | 2000-08-31 | — | — | WO | claimed |
| CN-1036394-C | Process for preparing quinolone derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-11-12 | — | — | CN | claimed |
| US-4880892-A | PHOSPHONIUM OR PHOSPHORANE CATALYST, PROTECTIVE COATINGS | CIBA-GEIGY CORPORATION (US) | 1989-11-14 | — | — | US | claimed |
| US-4562449-A | COLOR FORMERS FOR PRESSURE SENSITIVE OR HEAT SENSITIVE RECORDING MATERIAL | CIBA-GEIGY CORPORATION (US) | 1985-12-31 | — | — | US | claimed |
| US-4503227-A | HEAT SENSITIVE OR PRESSURE SENSITIVE RECORDING | CIBA-GEIGY CORPORATION (US) | 1985-03-05 | — | — | US | claimed |
| US-4094811-A | REDUCING SILVER SALTS IN THE PRESENCE OF A HETEROCYCLIC 5- OR 6-MEMBERED NITROGEN COMPOUND | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1978-06-13 | — | — | US | claimed |