SCHEMBL345294

SCHEMBL345294

CC(=CC(F)C(F)F)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.37
APEX1 P27695 8/20 0.34
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346579 0.86 AKR1C3 (0.34) AKR1C3APEX1PTGS1
SCHEMBL3417529 0.84 AKR1C3 (0.33) AKR1C3APEX1
SCHEMBL8474559 0.79
SCHEMBL2966908 0.79
SCHEMBL3859913 0.77
SCHEMBL9182216 0.76 ALDH1A1 (0.32) AKR1C3APEX1
SCHEMBL9182223 0.76 ALDH1A1 (0.32) AKR1C3APEX1
SCHEMBL9820833 0.75
SCHEMBL1623308 0.73 ALDH1A1 (0.32) AKR1C3APEX1PTGS1
SCHEMBL1623993 0.73 PTGS1 (0.35) AKR1C3APEX1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252568-B2 Silicone copolymer surface additive XEROX CORPORATION (US) 2025-03-18 US claimed
US-12023641-B2 Composition comprising self-stratifying amphiphilic Janus particles IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2024-07-02 US claimed
US-11815851-B2 Toner compositions and additives XEROX CORPORATION (US) 2023-11-14 US claimed
US-20230159683-A1 Silicone Copolymer Surface Additive XEROX CORPORATION 2023-05-25 US claimed
US-20230142857-A1 COMPOSITION COMPRISING SELF-STRATIFYING AMPHIPHILIC JANUS PARTICLES IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-05-11 US claimed
US-11612871-B2 Composition comprising self-stratifying amphiphilic Janus particles IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-03-28 US claimed
US-20220308487-A1 TONER COMPOSITIONS AND ADDITIVES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2022-09-29 US claimed
EP-2836550-B1 POLYCARBONATE BLEND AND METHOD OF PRODUCING THE SAME ROHM & HAAS (US) 2021-10-20 EP claimed
EP-2836548-B1 POLYCARBONATE BLEND ARTICLES AND METHOD OF PRODUCING THE SAME ROHM & HAAS (US) 2019-06-12 EP claimed
EP-3474075-A1 METALLIC TONER CARRIER Xerox Corporation (US) 2019-04-24 EP claimed
US-5998076-A Carrier XEROX CORPORATION (US) 1999-12-07 US claimed
US-5928832-A Toner adsorption processes XEROX CORPORATION (US) 1999-07-27 US claimed
WO-1998010916-A1 A NOVEL PRODUCTION METHOD FOR OBJECTS WITH RADIALLY-VARYING PROPERTIES UNIVERSITY OF FLORIDA (US) 1998-03-19 WO claimed
US-5567562-A Coated carrier particles and processes thereof XEROX CORPORATION (US) 1996-10-22 US claimed
US-5518855-A DIELECTRIC AND CONDUCTIVE POLYMER PAIRS XEROX CORPORATION (US) 1996-05-21 US claimed
US-5496675-A Carrier coating and processes XEROX CORPORATION (US) 1996-03-05 US claimed
US-5213938-A Oxidation of toner compositions XEROX CORPORATION (US) 1993-05-25 US claimed
EP-0100381-B1 SOFT CONTACT LENS HOYA CORPORATION (JP) 1986-09-17 EP claimed
US-4557562-A FLUOROALKYLMETHACRYLATE AND ACRYLIC ACID POLYMERS DAIKIN KOGYO CO., LTD. (JP) 1985-12-10 US claimed
EP-0100381-A1 Soft contact lens HOYA CORPORATION (JP) 1984-02-15 EP claimed