Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453406 | 1.00 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL4063697 | 0.98 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL4063689 | 0.98 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL30418037 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL2898862 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL3778455 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL3778451 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL2511411 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL2511413 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL3023676 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820666-B2 | Tetrahydrotriazolopyrazine derivatives and uses thereof | CONCERT PHARMACEUTICALS, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| WO-2008141021-A1 | DEUTERATED DERIVATIVES OF TETRAHYDROTRIAZOLOPYRAZINE COMPOUNDS AND THEIR USE AS DPP-IV INHIBITORS | CONCERT PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20080280913-A1 | TETRAHYDROTRIAZOLOPYRAZINE DERIVATIVES AND USES THEREOF | CONCERT PHARMACEUTICALS, INC. | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280913-A1 | TETRAHYDROTRIAZOLOPYRAZINE DERIVATIVES AND USES THEREOF | DPP4, DPP3, DPP7 | ALDH1A1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.