Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478074 | 0.92 | RECQL (0.41) | RECQLMAPK1HSD17B10POLBHTT | |
| SCHEMBL20787653 | 0.84 | STS (0.30) | — | |
| SCHEMBL12669990 | 0.78 | RECQL (0.41) | RECQLMAPK1HSD17B10POLBHTT | |
| SCHEMBL31243189 | 0.78 | RECQL (0.38) | RECQLMAPK1HSD17B10POLBHTT | |
| SCHEMBL3674965 | 0.76 | MAPK1 (0.44) | RECQLMAPK1HSD17B10POLBHTT | |
| SCHEMBL4338726 | 0.74 | P2RY6 (0.37) | HSD17B10 | |
| SCHEMBL29260495 | 0.72 | RECQL (0.39) | RECQLMAPK1HSD17B10POLBHTT | |
| SCHEMBL4102660 | 0.72 | RECQL (0.39) | RECQLMAPK1HSD17B10POLBHTT | |
| SCHEMBL14774812 | 0.72 | KDM4E (0.37) | MAPK1POLBHTTMEN1KMT2A | |
| SCHEMBL13816563 | 0.72 | MAPK1 (0.35) | RECQLMAPK1HSD17B10POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820709-B2 | N-phenylpyrazole derivatives as pesticides | MERIAL LIMITED (US) | 2010-10-26 | — | — | US | disclosed |
| US-20070281987-A1 | N-phenylpyrazole derivatives as pesticides | MERIAL, INC. | 2007-12-06 | — | — | US | disclosed |
| EP-1761501-A1 | USE OF N-PHENYLPYRAZOLE DERIVATIVES AS PESTICIDES | Merial Ltd. (US) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006000314-A1 | N-PHENYLPYRAZOLE DERIVATIVES AS PESTICIDES | MERIAL LTD. (US) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281987-A1 | N-phenylpyrazole derivatives as pesticides | ACHE, CYP3A5, PTMS | RECQL 3364/4885MAPK1 2169/4885HSD17B10 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.