Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435489 | 0.87 | KMT2A (0.36) | KMT2ATARDBPCYP3A4CYP2C19SOAT1 | |
| SCHEMBL26307850 | 0.82 | KMT2A (0.40) | KMT2ATARDBPCYP3A4CYP2C19SOAT1 | |
| SCHEMBL22472188 | 0.77 | CA1 (0.33) | — | |
| SCHEMBL18526803 | 0.77 | CYP1A2 (0.37) | KMT2ACYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL7941385 | 0.75 | UGT2B7 (0.32) | KDM4E | |
| SCHEMBL15299925 | 0.73 | KDM5A (0.43) | KMT2AMEN1KDM5AKDM7AKDM4C | |
| SCHEMBL15299922 | 0.73 | KDM5A (0.43) | KMT2AMEN1KDM5AKDM7AKDM4C | |
| SCHEMBL10423804 | 0.73 | KDM5A (0.43) | KMT2AMEN1KDM5AKDM7AKDM4C | |
| SCHEMBL9063104 | 0.73 | TSHR (0.40) | KMT2AMEN1KDM5AKDM7AKDM4C | |
| SCHEMBL15300098 | 0.73 | KDM5A (0.43) | KMT2AMEN1KDM5AKDM7AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205256-A2 | REAGENTS FOR INDUCING AN IMMUNE RESPONSE | Dana-Faber Cancer Institute, Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009042895-A2 | REAGENTS FOR INDUCING AN IMMUNE RESPONSE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2009-04-02 | — | — | WO | disclosed |