SCHEMBL8435489

SCHEMBL8435489

CN1C(C)(C)CC(CCCCCCCCCCCCCCCCCC(N)=O)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
TARDBP Q13148 1/20 0.36
KDM5A P29375 4/20 0.33
PHF8 Q9UPP1 4/20 0.33
KDM2A Q9Y2K7 4/20 0.33
KDM4C Q9H3R0 3/20 0.33
KDM7A Q6ZMT4 1/20 0.33
SOAT1 P35610 2/20 0.33
MEN1 O00255 1/20 0.33
FAAH O00519 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
ABHD16A O95870 1/20 0.31
KDM4A O75164 1/20 0.31
AR P10275 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15299882 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL3453898 0.87 KMT2A (0.36) KMT2ATARDBPKDM5APHF8KDM2A
SCHEMBL15707713 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL10424780 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL10423804 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL15300078 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL15300098 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL15299925 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL15299922 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C
SCHEMBL15299835 0.87 KDM5A (0.43) KMT2AKDM5APHF8KDM2AKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641822-B1 Thermoplastic resin composition SUMITOMO CHEMICAL CO (JP) 1999-12-01 EP disclosed
US-5478873-A Polyphenylene ether resin stabilized by 4-amino-2,2,6,6-tetramethylpiperidyl compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-12-26 US disclosed
EP-0641822-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-08 EP disclosed