SCHEMBL345392

SCHEMBL345392

BrCc1cscn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243566 0.76
SCHEMBL1190495 0.74
SCHEMBL243565 0.74
SCHEMBL7352430 0.74
Hydrochloric Acid SCHEMBL122926 0.72
Hydrochloric Acid SCHEMBL6941733 0.72
SCHEMBL21419814 0.72
SCHEMBL18410597 0.70
SCHEMBL22593336 0.70
Benzene SCHEMBL10825584 0.70 SLC6A3 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624024-B2 EP2 antagonist compounds RESERVOIR NEUROSCIENCE, INC. (US) 2026-05-12 US disclosed
CN-119019364-A Uracil derivative and preparation method and application thereof 石河子大学 2024-11-26 CN disclosed
US-20240182459-A1 EP2 ANTAGONIST COMPOUNDS RESERVOIR NEUROSCIENCE, INC. 2024-06-06 US disclosed
EP-4359392-A1 EP2 ANTAGONIST COMPOUNDS Reservoir Neuroscience, Inc. (US) 2024-05-01 EP disclosed
WO-2022272060-A1 EP2 ANTAGONIST COMPOUNDS RESERVOIR NEUROSCIENCE, INC. (US) 2022-12-29 WO disclosed
WO-2022272060-A1 EP2 ANTAGONIST COMPOUNDS RESERVOIR NEUROSCIENCE, INC. (US) 2022-12-29 WO disclosed
WO-2021096314-A1 NOVEL BENZIMIDAZOLE DERIVATIVE AND USE THEREOF 가천대학교 산학협력단 2021-05-20 WO disclosed
CN-110300590-A TYK2 inhibitor and application thereof 林伯士拉克许米公司 2019-10-01 CN disclosed
EP-2432776-B1 METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS UNIV LAVAL (CA) 2019-09-11 EP disclosed
US-9315521-B2 Pyrimidines as novel therapeutic agents UNIVERSITé LAVAL (CA) 2016-04-19 US disclosed
WO-1995013069-A1 PIPERIDINES, PYRROLIDINES AND HEXAHYDRO-1H-AZEPINES PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO., INC. (US) 1995-05-18 WO disclosed
US-4973684-A Cephem compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-11-27 US disclosed
US-4912212-A Cephem compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-03-27 US disclosed
US-4668783-A Thiazolylacetamido cephalosporin compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-05-26 US disclosed
US-4514565-A Thiazolylacetamido cephalosphorin compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-04-30 US disclosed
US-4355160-A Thiazolylacetamido cephalosporin type compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-10-19 US disclosed
US-4298606-A Thiazolylacetamido compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-11-03 US disclosed
US-4205180-A CHEMICAL INTERMEDIATES FOR NOVEL CEPHALOSPORIN COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-05-27 US disclosed
US-4203899-A Thiazolylacetamido compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-05-20 US disclosed
US-4098888-A THIAZOLYLACETAMIDO CEPHALOSPORIN TYPE COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-07-04 US disclosed