⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948490 | 0.77 | — | — | |
| SCHEMBL18806384 | 0.77 | — | — | |
| SCHEMBL2188532 | 0.77 | — | — | |
| SCHEMBL19397678 | 0.77 | — | — | |
| SCHEMBL9601137 | 0.76 | — | — | |
| SCHEMBL526443 | 0.75 | — | — | |
| SCHEMBL8852170 | 0.74 | — | — | |
| SCHEMBL8494011 | 0.72 | — | — | |
| SCHEMBL19016291 | 0.72 | — | — | |
| SCHEMBL19477582 | 0.72 | TRPM8 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381142-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | US | claimed |
| WO-2023230217-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | WO | claimed |
| WO-2023230217-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | WO | disclosed |
| US-20230381142-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | US | disclosed |
| WO-2014160811-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |
| EP-2240177-A2 | TREATMENTS FOR NEUROPATHY | Children's Medical Center Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| CN-101043918-B | Cationic azacyanine dyes and colorants containing said dyes | PROCTER & GAMBLE | 2010-05-26 | — | — | CN | disclosed |
| WO-2009102570-A2 | TREATMENTS FOR NEUROPATHY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-08-20 | — | — | WO | disclosed |
| CN-101076571-A | Cationic azoazine dyes and colorants containing said compounds | PROCTER & GAMBLE (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-101043918-A | Cationic azacyanine dyes and colorants containing said dyes | PROCTER & GAMBLE (US) | 2007-09-26 | — | — | CN | disclosed |