Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NAMPT | P43490 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22221563 | 0.77 | CYP1A2 (0.89) | CYP1A2CYP3A4CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL1823231 | 0.73 | CNR1 (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL1819151 | 0.72 | CNR1 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL1464914 | 0.71 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL391683 | 0.71 | RAB9A (0.78) | CYP1A2CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL1817637 | 0.71 | KMT2A (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL10978857 | 0.70 | CYP11B1 (1.00) | CYP11B1CYP11B2RAB9ANAMPTMEN1 | |
| SCHEMBL1823516 | 0.69 | PPARA (0.45) | CYP1A2CYP3A4CYP2C19RAB9AMEN1 | |
| SCHEMBL9190814 | 0.69 | KMT2A (1.00) | CYP11B1CYP11B2RAB9ANAMPTMEN1 | |
| SCHEMBL8941244 | 0.69 | MEN1 (0.82) | CYP1A2CYP3A4CYP2C9CYP2C19CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816382-B2 | Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-19 | — | — | US | disclosed |
| US-20070004677-A1 | Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004677-A1 | Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition | P2RY1, P2RY11, UTS2R | CYP1A2 2944/4885CYP3A4 2077/4885CYP2C9 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.