Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454417 | 0.87 | SCD (0.59) | SCDPPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL3455092 | 0.87 | PPARD (0.56) | SCDPPARAMAPTCHRM4LMNA | |
| SCHEMBL3051532 | 0.86 | SCD (0.64) | SCDCHRM4SMN1; SMN2 | |
| SCHEMBL13541845 | 0.86 | PPARA (0.60) | SCDPPARACHRM4LMNAHTT | |
| SCHEMBL244641 | 0.85 | SCD (0.58) | SCDPPARAMAPTCHRM4LMNA | |
| SCHEMBL3042709 | 0.84 | CHRM4 (0.57) | SCDPPARAMAPTCHRM4LMNA | |
| SCHEMBL13541865 | 0.82 | PPARA (0.48) | SCDPPARAMAPTCHRM4LMNA | |
| SCHEMBL3458722 | 0.81 | ATM (0.53) | SCDMAPTCHRM4HTTSMN1; SMN2 | |
| SCHEMBL13541868 | 0.80 | PPARA (0.69) | SCDPPARAMAPT | |
| SCHEMBL3045493 | 0.80 | SCD (0.62) | SCDPPARAMAPTCHRM4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |