Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454547 | 0.81 | SCD (0.57) | KMT2ASCDCHRM4HTTMAPT | |
| SCHEMBL3051532 | 0.80 | SCD (0.64) | SCDNPC1RAB9AHPGDCHRM4 | |
| SCHEMBL3455193 | 0.77 | ATM (0.46) | ATMMEN1KMT2AGAASCD | |
| SCHEMBL3448031 | 0.77 | SCD (0.55) | MEN1KMT2ASCDNPC1RAB9A | |
| SCHEMBL13541934 | 0.77 | MEN1 (0.53) | MEN1KMT2ASCDNPC1ALDH1A1 | |
| SCHEMBL12852314 | 0.76 | ATM (0.84) | ATMMEN1KMT2AGAAKLKB1 | |
| SCHEMBL3455092 | 0.75 | PPARD (0.56) | MEN1KMT2AGAASCDRAB9A | |
| SCHEMBL13541845 | 0.74 | PPARA (0.60) | ATMSCDPKMHPGDCHRM4 | |
| SCHEMBL3448039 | 0.74 | SCD (0.44) | ATMMEN1KMT2ASCDNPC1 | |
| SCHEMBL3454417 | 0.73 | SCD (0.59) | SCDNPC1RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |