Phthalic Acid

Phthalic Acid

SCHEMBL3454567

COC(=O)c1ccc(C(=O)OC)cc1.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.72
RAB9A P51151 4/20 0.61
MAPT P10636 3/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
CASP3 P42574 1/20 0.61
SENP8 Q96LD8 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
SENP6 Q9GZR1 1/20 0.61
ALDH1A1 P00352 4/20 0.58
ALOX15 P16050 1/20 0.58
SLC6A3 Q01959 1/20 0.58
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
TDP1 Q9NUW8 1/20 0.57
CA12 O43570 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
KMT2A Q03164 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Benzoylbenzoic Acid SCHEMBL31198998 0.89 AKR1C3 (0.71) TSHRRAB9AMAPTL3MBTL1CASP3
SCHEMBL8855891 0.87 ALDH1A1 (0.64) TSHRMAPTALDH1A1ALOX15SLC6A3
SCHEMBL31440979 0.87 ALDH1A1 (0.64) TSHRMAPTALDH1A1ALOX15SLC6A3
SCHEMBL40534 0.87 ALDH1A1 (0.64) TSHRMAPTALDH1A1ALOX15SLC6A3
Dimethyl Phthalate SCHEMBL9436120 0.87 ALDH1A1 (0.64) TSHRMAPTALDH1A1ALOX15SLC6A3
Dimethyl Phthalate SCHEMBL28932346 0.87 ALDH1A1 (0.64) TSHRMAPTALDH1A1ALOX15SLC6A3
SCHEMBL29658803 0.87 ALDH1A1 (0.64) TSHRMAPTALDH1A1ALOX15SLC6A3
Methyl Benzoate SCHEMBL28249321 0.87 TSHR (0.95) TSHRRAB9AMAPTL3MBTL1CASP3
Benzene SCHEMBL28351738 0.87 TSHR (0.85) TSHRRAB9AMAPTL3MBTL1CASP3
SCHEMBL25314257 0.87 SMN1; SMN2 (0.68) RAB9AMAPTL3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816008-B2 Compartmentalized resin pellets M & G USA CORPORATION (US) 2010-10-19 US disclosed
US-20090239077-A1 Compartmentalized Resin Pellets M&G USA CORPORATION 2009-09-24 US disclosed
US-7550203-B2 Compartmentalized resin pellets M & G USA CORPORATION (US) 2009-06-23 US disclosed
US-7541091-B2 Compartmentalized resin pellets for oxygen scavenging M & G USA CORPORATION (US) 2009-06-02 US disclosed
US-20060205853-A1 Compartmentalized resin pellets for oxygen scavenging M&G USA CORPORATION 2006-09-14 US disclosed
US-20050261126-A1 Compartmentalized resin pellets M&G USA CORPORATION 2005-11-24 US disclosed