Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.73 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | DRD1 | P21728 | 2/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | DRD5 | P21918 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | APEX1 | P27695 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21002056 | 0.88 | BACE1 (0.55) | BACE1ALOX15 | |
| SCHEMBL6561766 | 0.87 | BACE1 (0.61) | BACE1TAAR1MAPK1KDM4EADRA2A | |
| SCHEMBL21067399 | 0.85 | BACE1 (1.00) | BACE1TAAR1MAPK1KDM4EADRA2A | |
| SCHEMBL5168102 | 0.84 | CNR1 (0.59) | BACE1KDM4EDRD2DRD1DRD4 | |
| SCHEMBL24648925 | 0.82 | BACE1 (0.59) | BACE1TAAR1MAPK1KDM4EADRA2A | |
| SCHEMBL14756852 | 0.82 | TAAR1 (0.64) | BACE1TAAR1MAPK1KDM4EADRA2A | |
| SCHEMBL3847706 | 0.82 | BACE1 (0.69) | BACE1TAAR1MAPK1KDM4EADRA2A | |
| SCHEMBL593741 | 0.81 | TRPA1 (0.67) | BACE1MAPK1KDM4EMAPTALDH1A1 | |
| Dopamine SCHEMBL11806773 | 0.81 | TAAR1 (0.81) | BACE1TAAR1MAPK1KDM4EADRA2A | |
| SCHEMBL5166205 | 0.81 | HTT (0.60) | BACE1MAPK1MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399697-B2 | Hardeners for epoxy resins, which comprise aromatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-07-26 | — | — | US | disclosed |
| US-9394399-B2 | Hardeners for epoxy resins, which comprise pyridinyl groups | SIKA TECHNOLOGY AG (CH) | 2016-07-19 | — | — | US | disclosed |
| US-20150259465-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2015-09-17 | — | — | US | disclosed |
| US-20140316080-A1 | HARDENERS FOR EPOXY RESINS, WHICH COMPRISE PYRIDINYL GROUPS | SIKA TECHNOLOGY AG (CH) | 2014-10-23 | — | — | US | disclosed |
| US-20140275446-A1 | HARDENERS FOR EPOXY RESINS, WHICH COMPRISE AROMATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2014-09-18 | — | — | US | disclosed |
| US-20100323202-A1 | USE OF CARBOXYLIC ACID HYDRAZIDE FOR DE-BONDING POLYURETHANE ADHESIVES | SIKA TECHNOLOGY AG (CH) | 2010-12-23 | — | — | US | disclosed |
| WO-2010146144-A2 | USE OF CARBOLIC ACID HYDRIDE FOR DEBONDING POLYURETHANE ADHESIVES | SIKA TECHNOLOGY AG (CH) | 2010-12-23 | — | — | WO | disclosed |