⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23425906 | 0.79 | CHRNB2 (0.46) | — | |
| SCHEMBL385837 | 0.76 | — | — | |
| SCHEMBL14175020 | 0.71 | — | — | |
| SCHEMBL12344858 | 0.71 | — | — | |
| SCHEMBL16837521 | 0.71 | CHRNB2 (0.41) | — | |
| SCHEMBL436448 | 0.71 | — | — | |
| SCHEMBL986680 | 0.71 | — | — | |
| SCHEMBL3454601 | 0.71 | — | — | |
| SCHEMBL11563132 | 0.69 | — | — | |
| SCHEMBL16439256 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666129-B1 | COMPOSITE POROUS MEMBRANE | ASAHI KASEI MEDICAL CO LTD (JP) | 2017-06-21 | — | — | EP | disclosed |
| WO-2014160811-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |
| EP-2039701-B1 | 20-Keto-11Beta-Arylsteroids and their Derivatives having agonist or antagonist hormonal activity | RES TRIANGLE INST (US) | 2014-04-23 | — | — | EP | disclosed |
| EP-2240177-A2 | TREATMENTS FOR NEUROPATHY | Children's Medical Center Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009102570-A2 | TREATMENTS FOR NEUROPATHY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-08-20 | — | — | WO | disclosed |
| EP-2039701-A2 | 20-keto-11beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties | RESEARCH TRIANGLE INSTITUTE (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1666129-A1 | COMPOSITE POROUS MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Asahi Kasei Kabushiki Kaisha (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-1060186-A4 | 20-KETO-11BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RES TRIANGLE INST (US) | 2005-05-04 | — | — | EP | disclosed |
| CN-1298409-A | 20-keto-11&beta, -arylsteroids and their derivatives having agonist or antagonist hormonal properties | RES TRIANGLE INST (US) | 2001-06-06 | — | — | CN | disclosed |
| EP-1060186-A1 | 20-KETO-11BETA-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RESEARCH TRIANGLE INSTITUTE (US) | 2000-12-20 | — | — | EP | disclosed |
| US-6020328-A | 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties | RESEARCH TRIANGLE INSTITUTE (US) | 2000-02-01 | — | — | US | disclosed |
| WO-1999045022-A1 | 20-KETO-11β-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES | RESEARCH TRIANGLE INSTITUTE (US) | 1999-09-10 | — | — | WO | disclosed |
| EP-0542369-B1 | Self-extinguishing polymeric compositions | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-05-13 | — | — | EP | disclosed |